Excessive use of pesticides

Interfere with cell respiration.
Inhibit sodium and potassium conduction in nerve cells and block nerve impulse transmission.
Inhibits acetaldehyde dehydrogenase, which is essential in conversion of acetaldehyde to acetic acid.
Inhibition of liver enzymes.
Blocks nerve impulse transmission. and
Inhibits cell respiration and blocks conduction of nerve impulses.
Effects of pesticides on human and environment
Immediate effects
Skin, mucous membrane, sensory and behavioral, depressed motor functions, motor weakness, vomiting and diarrhea.
Long term effects
Memory loss, confusion, behavioral defects, carcinogens, cataract, bone marrow, liver and testicular damage, heart, immunotoxins.
Environment effects
Teratogen to fish, earthworms, bees, aquatic arthropods.
Why and when pesticides become toxic
Human beings use antibiotics to kill microorganisms. in a similar manner pesticides are used to kill insects, fungi and other pests which damage human food. Antibiotics, utilized by humans also produce side effects. in a similar way pesticides also produce some side effects. There is difference in the two. side effects of the antibiotics are usually experienced by those who take these antibiotics while the side effects of the pesticides affect the environment as they are distributed widely in the air, most of the time.
To inform the public and an ordinary citizen about the level of danger potentially existing in some of the chemicals and especially pesticides, the US Environment Protection Agency (EPA) provides guidance. The agency places a label which carries information related to the danger present. The level ranges from caution to warning to danger. caution means the lowest level of threat of poison (toxicity category I),…
There is variety of pesticides available in the market. The sole purpose of their use is to control different types of insects, weeds, pests and molds wither in and around houses (the lawns, small gardens) or in the farm which is the largest use. They act like antibiotics in human but their side effects are wide spread as their use is not localized because they affect the surrounding environment to a greater extent. The US EPA regulates the use of pesticides along with other chemicals. The same agency also determines the risk a specific chemical can produce to a human body. This risk may occur to the occasional users in the houses or frequent users in the farms. This risk may range from a simple allergic episode to spontaneous abortions in pregnant women or cancer. The exposure to pesticides may result in some morbid conditions which may range from mild allergic reactions which may get prolonged to some real long term problems, either in the shape of some cancers or when a pregnant woman gets exposed to these chemicals then even the developing fetus faces a greater risk. In a case control study carried out by Hoppin et al to compare the effect of pesticides on women with two different types of asthma, atopic and non atopic.They found that those women who had grown up in the farm had stronger association with pesticides. This association was found for atopic asthma while those women who did not apply these pesticides or not grown up in the farm were not found to be associated with atopic asthma.