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The Ghent Altarpiece or officially known as the Adoration of the Mystic Lamb was started by Flemish artist Hubert van Eyck and completed by his brother Jan van Eyck in 1432. This twenty-four panel painting depicting the early stages in the life of Jesus is considered one of the famous works of Jan van Eyck. It can be viewed in two ways: open on feast days and close on weekdays. When opened, the upper center panel depicts three central figures, the Virgin Mary, God the Father, and John the Baptist with the singing angels, Adam and Eve on the sides. The lower center panel shows the adoration of the Lamb of God with the martyrs, writers, prophets, saints and the pope on the sides. When closed, the upper panels depict the two sibyls and the prophets Zaccariah and Micah, the middle four panels show the annunciation to Mary, while the lower panels depict Saints John the Baptist and John the Evangelist. The altarpiece showcases much detail works not just in religious themes but also in earthly things like trees and other foliage manifesting the growing awareness towards natural elements. The presence of the images of the donors, a merchant named Jodocus Vijd and his wife Lysbette Borluut seen on the lower portion when the panel is closed, is also a manifest that iconic elements are not solely the focal point during the latter part of the Byzantine period, but patronage is greatly revered too. Today, the altar piece is located in Saint Bavo Cathedral, Ghent, Belgium.
The Annunciation and the Nativity, a detail of the marble relief of the pulpit of the Pisa Cathedral baptistery made by Nicola Pisano from 1259-1260 depicts the naturalism style like human emotion and expression. In spite of the religious context of the sculpture, it depicts a return to classical artistry showcased in the deeply natural and human physicality of the figures.
The Virgin of the Rocks oil painted on panel by Leonardo Da Vinci completed sometime in 1485 tells the story of the